Drugs for Hypertension
May 1, 2014 (Issue: 141)
Most recent guidelines recommend a BP goal of 140/90 mm Hg. For patients ≥60 years old without diabetes
or chronic kidney disease, one guideline recommends
150/90 mm Hg both as the drug treatment initiation
threshold and treatment target; this...more
1. National Institute for Health and Clinical Excellence. Hypertension: clinical management of primary hypertension in adults. National Institute for Health and Clinical Excellence 2011. Available at: http://www.nice.org.uk/. Accessed April 7, 2014.
2. WS Aronow et al. ACCF/AHA 2011 expert consensus document on hypertension in the elderly: a report of the American College of Cardiology Foundation Task Force on Clinical Expert Consensus documents developed in collaboration with the American Academy of Neurology, American Geriatrics Society, American Society for Preventive Cardiology, American Society of Hypertension, American Society of Nephrology, Association of Black Cardiologists, and European Society of Hypertension. J Am Coll Cardiol 2011; 57:2037.
3. G Mancia et al. 2013 ESH/ESC Guidelines for the management of arterial hypertension: the Task Force for the management of arterial hypertension of the European Society of Hypertension (ESH) and of the European Society of Cardiology (ESC). J Hypertens 2013; 31:1281.
4. PA James et al. 2014 evidence-based guideline for the management of high blood pressure in adults: report from the panel members appointed to the Eighth Joint National Committee (JNC 8). JAMA 2014; 311:507.
5. MA Weber et al. Clinical practice guidelines for the management of hypertension in the community: a statement by the American Society of Hypertension and the International Society of Hypertension. J Clin Hypertens (Greenwich) 2014; 16:14.
6. The 2014 Canadian Hypertension Education Program (CHEP) recommendations. Available at http://www.hypertension.ca/en/chep. Accessed April 7, 2014.
7. KDIGO clinical practice guideline for the management of blood pressure in chronic kidney disease. Available at: http://www.kdigo.org. Accessed April 7, 2014.
8. Executive summary: standards of medical care in diabetes — 2014. Diabetes Care 2014; 37(Suppl 1):S5.
9. JT Wright Jr et al. Evidence supporting a systolic blood pressure goal of less than 150 mm Hg in patients aged 60 years or older: the minority view. Ann Intern Med 2014; 160:499.
10. JB Kostis et al. Association between chlorthalidone treatment of systolic hypertension and long-term survival. JAMA 2011; 306:2588.
11. JT Wright Jr et al. ALLHAT findings revisited in the context of subsequent analyses, other trials, and meta-analyses. Arch Intern Med 2009; 169:832.
12. ME Ernst and M Moser. Use of diuretics in patients with hypertension. N Engl J Med 2009; 361:2153.
13. NS Beckett et al. Treatment of hypertension in patients 80 years of age or older. N Engl J Med 2008; 358:1887.
14. DA Calhoun et al. Refractory hypertension: determination of prevalence, risk factors, and comorbidities in a large, population-based cohort. Hypertension 2014; 63:451.
15. Drugs for chronic heart failure. Treat Guidel Med Lett 2012; 10:69.
16. Aliskiren (Tekturna) for hypertension. Med Lett Drugs Ther 2007; 49:29.
17. HH Parving et al. Cardiorenal end points in a trial of aliskiren for type 2 diabetes. N Engl J Med 2012; 367:2204.
18. Aliskiren trial terminated. Med Lett Drugs Ther 2012; 54:5.
19. F Turnbull et al. Effects of different blood-pressure-lowering regimens on major cardiovascular events: results of prospectively-designed overviews of randomised trials. Lancet 2003; 362:1527.
20. K Jamerson et al. Benazepril plus amlodipine or hydrochlorothiazide for hypertension in high-risk patients. N Engl J Med 2008; 359:2417.
21. WH Frishman and E Saunders. ß-adrenergic blockers. J Clin Hypertens (Greenwich) 2011; 13:649.
22. CS Wiysonge et al. Beta-blockers for hypertension. Cochrane Database Syst Rev 2012; 8:CD002003.
23. GL Bakris et al. Metabolic effects of carvedilol vs metoprolol in patients with type 2 diabetes mellitus and hypertension: a randomized controlled trial. JAMA 2004; 292:2227.
24. Nebivolol (Bystolic) for hypertension. Med Lett Drugs Ther 2008; 50:17.
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