Influenza is generally a self-limited illness, but complications including pneumonia, respiratory failure, and death can occur, especially in persons at increased risk (see Table 1).
TREATMENT OF INFLUENZA — Three neuraminidase inhibitors (oral oseltamivir, IV peramivir, and inhaled zanamivir) and the oral cap-dependent endonuclease inhibitor baloxavir marboxil are available in the US and are recommended for treatment of influenza this season (see Table 2).1
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Acetaminophen has been considered the drug of choice for treatment of fever and pain during pregnancy for decades, but a recent announcement by the US Department of Health and Human Services (HHS) has prompted discussion about its effects on fetal neurodevelopment and the risk of autism.
THE ANNOUNCEMENT — The HHS announcement claims that chronic acetaminophen use in pregnant women, especially late in pregnancy, may cause long-term neurological effects such as autism in their children.1 It cites a "consensus statement" that calls for minimizing use of acetaminophen during pregnancy.2 This statement has not been endorsed by any professional organizations and has been criticized for misrepresenting the studies that it references and failing to account for potential confounding variables.3
In conjunction with the HHS announcement, the FDA has issued a letter to physicians stating that it will …